Which assays are used in the diagnosis of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Various assays for stress protein genes, glycosaminoglycans, mast cell tryptase, Tamm-Horsfall protein autoantibodies, and others have been suggested by numerous investigators. However, these assays are currently used primarily for research purposes and do not have a defined role in the diagnosis of interstitial cystitis. Antiproliferative factor (APF) has shown promise in research assays as a biomarker for worsened disease and is currently being investigated as a clinical marker. [8, 9]


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