What are the racial predilections of protein C deficiency?

Updated: Jan 04, 2019
  • Author: Shamudheen Rafiyath, MD; Chief Editor: Perumal Thiagarajan, MD  more...
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Answer

Congenital protein C deficiency is recognized as a cause of thrombophilia around the world. Studies in blacks and Asians suggest that its prevalence in these populations is on par with its frequency of occurrence in whites. [48, 49] In contrast, the factor V Leiden and prothrombin gene mutations (see Hereditary and Acquired Hypercoagulability) occur with substantially greater frequency in white than in nonwhite populations.


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