What is the role of imaging studies in the workup of acute intermittent porphyria (AIP)?

Updated: Jul 08, 2020
  • Author: Thomas G DeLoughery, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Imaging studies are usually not helpful. Abdominal films will sometimes demonstrate an ileus. Findings on cranial computed tomography (CT) scan are normal.

Brain magnetic resonance imaging (MRI) scans occasionally show signs of increased edema in patients having very severe attacks. In patients with seizures, MRI may demonstrate parieto-occipital gyriform lesions on T2-weighted images that are characteristic of posterior reversible encephalopathy syndrome (PRES). [11]


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