What is the role of hyperbaric oxygen therapy in the treatment of necrotizing fasciitis?

Updated: Sep 02, 2020
  • Author: Steven A Schulz, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Once other modalities, including surgical debridement and antibiotic administration, have been used, hyperbaric oxygen therapy (HBOT) may be considered, if available. [103, 55, 104] The literature suggests that HBOT can reduce mortality when used as part of an aggressive treatment regimen for necrotizing fasciitis. [105, 60, 106, 69, 107]

Well-controlled, randomized, clinical trials demonstrating a statistically significant benefit of HBOT are lacking, however, and consequently its use as an adjunctive therapy for necrotizing fasciitis remains controversial. [108, 109, 110] Transfer to a hospital equipped with HBOT should not delay emergency surgical intervention.

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