Which factors are associated with poor outcome for necrotizing fasciitis?

Updated: Sep 02, 2020
  • Author: Steven A Schulz, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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A study by Friederichs et al indicated that necrotizing fasciitis tends to have a worse outcome when acquired iatrogenically via injection or infiltration than it does when acquired in other ways, with higher mortality and amputation rates (67% and 73%, respectively) found. The study included 21 patients with injection- or infiltration-related necrotizing fasciitis and 134 patients who were infected with the condition through other means. [56]

In a study by Rouse et al, the overall mortality rate was 73% (20 of 27 patients). They indicated that prompt recognition and treatment of necrotizing fasciitis was essential: Of 12 patients whose treatment was delayed for more than 12 hours, 11 patients died. [35]

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