What are poor prognostic factors in necrotizing fasciitis?

Updated: Sep 02, 2020
  • Author: Steven A Schulz, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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In another study, preexisting chronic liver dysfunction, chronic renal failure, thrombocytopenia, hypoalbuminemia, and postoperative dependence on mechanical ventilation represented poor prognostic factors in monomicrobial necrotizing fasciitis. In addition, patients with gram-negative monobacterial necrotizing fasciitis had more fulminant sepsis. [52]

Similarly, a retrospective study by Adachi et al reported that in patients with necrotizing fasciitis, renal dysfunction predicts fatal outcomes. Estimated glomerular filtration rate was a prognostic factor, the cutoff value being 20.6 mL/min. [53]

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