Which conditions should be included in the differential diagnoses of polycythemia vera (PV) in patients with PH-negative MPD?

Updated: Sep 20, 2021
  • Author: Srikanth Nagalla, MD, MS, FACP; Chief Editor: Sara J Grethlein, MD, FACP  more...
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Diagnostic laboratory tests have been developed to increase the ability to identify primary myeloproliferative diseases (MPDs) and to differentiate them from reactive conditions associated with increased blood cell levels, which can mimic MPDs. Once an MPD (Philadelphia chromosome negative [Ph–]) is documented, it must be differentiated from the following conditions, which have manifestations that overlap with polycythemia vera (PV):

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