What are the Portland Protocol Titration Guidelines for IV insulin therapy if the blood glucose level is less than 70 mg/dL?

Updated: Nov 06, 2018
  • Author: Guy W Soo Hoo, MD, MPH; Chief Editor: George T Griffing, MD  more...
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Blood glucose level - 70 mg/dL

  • If not alert or nothing by mouth, administer 15 mL of D50W intravenously; if blood glucose is less than 40 mg/dL, administer 25 mL of D50W intravenously.

  • If alert and able to take by mouth, give 8 oz of juice or 6 glucose tablets orally.

  • Recheck blood glucose levels every 30 minutes until more than 100 mg/dL.

  • If the next blood glucose level is less than 60 mg/dL, double the amount of the previous treatment.

  • If the next blood glucose level is 60-70 mg/dL, repeat the treatment.

  • When blood glucose is more than 125 mg/dL, restart insulin rate at 50% of previous rate and recheck blood glucose in 30 minutes.

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