Which factors affect point-of-care blood glucose measurements in IV insulin therapy?

Updated: Nov 06, 2018
  • Author: Guy W Soo Hoo, MD, MPH; Chief Editor: George T Griffing, MD  more...
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Answer

Answer

Factors affecting point-of-care blood glucose measurements include the following: [9]

  • Source of blood (serum, plasma, whole blood)

  • Sampling site (capillary blood, venous blood, arterial blood)

  • Amount of blood on glucometer strip

    • Excess blood (spurious high readings)

    • Insufficient blood (spurious low readings)

  • Anemia (spuriously high levels in whole blood assays)

  • Peripheral hypoperfusion (shock, vasoconstriction, vasospastic disorders, dehydration)

  • Delay in sample processing

  • Substances that interfere with glucose measurements

    • Levodopa

    • Dopamine

    • Mannitol

    • Acetaminophen

    • High unconjugated bilirubin

    • Severe lipemia

    • High uric acid

    • Maltose (found in immunoglobulin solutions)

    • Icodextrin (found in peritoneal dialysis fluid)


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