What are the nonoperative treatments for epistaxis in to Osler-Weber-Rendu disease (OWRD) (hereditary hemorrhagic telangiectasia [HHT])?

Updated: Oct 06, 2020
  • Author: Klaus-Dieter Lessnau, MD, FCCP; Chief Editor: Vincent Lopez Rowe, MD  more...
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Answer

Epistaxis is often recurrent, necessitating multiple treatments. Moderate and mild epistaxis can be treated medically or with endoscopic ablation; severe epistaxis calls for surgical treatment.

Nonoperative treatment of epistaxis may include the following:

  • Iron supplementation
  • Humidification
  • Packing
  • Transfusion
  • Estrogen therapy
  • Aminocaproic acid
  • Electrocautery and argon beam ablation
  • Neodymium:yttrium-aluminum-garnet (Nd:YAG) laser ablation [106]
  • Thalidomide

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