What are the National Comprehensive Cancer Network (NCCN) criteria for a diagnosis of active multiple myeloma (MM)?

Updated: May 11, 2021
  • Author: Dhaval Shah, MD; Chief Editor: Emmanuel C Besa, MD  more...
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The current diagnostic criteria for symptomatic multiple myeloma are as follows [131] :

  • Clonal bone marrow plasma cells ≥10% or bony or extramedullary plasmacytoma (confirmed by biopsy)
  • One or more myeloma-defining events.

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