What is the efficacy of bortezomib in the treatment of refractory multiple myeloma (MM)?

Updated: Sep 30, 2019
  • Author: Dhaval Shah, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Bortezomib has a well-established role as salvage therapy, based on a phase III randomized trial showing a response rate of 38% versus 18% in patients receiving dexamethasone only. [49] Median progression-free survival was 6.22 months in the bortezomib arm versus 3.49 months in the dexamethasone-only group.


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