Which physical findings suggest amyloidosis in multiple myeloma (MM)?

Updated: May 11, 2021
  • Author: Dhaval Shah, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Amyloidosis may develop in some patients with MM. The characteristic physical examination findings that suggest amyloidosis include the following:

  • Shoulder pad sign
  • Macroglossia
  • Typical skin lesions
  • Post-proctoscopic peripalpebral purpura

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