Which chemotherapy regimens are used in the treatment of multiple myeloma (MM)?

Updated: May 11, 2021
  • Author: Dhaval Shah, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Several drug therapies are valuable in the treatment of symptomatic MM. Clinicians treat many patients with high-dose therapy and peripheral blood or bone marrow stem cell transplantation.

Chemotherapy regimens used in patients with MM include the following:

  • Thalidomide, either as a single agent or in combination with steroids or with melphalan
  • Lenalidomide plus dexamethasone
  • Bortezomib plus melphalan
  • VAD (vincristine, doxorubicin [Adriamycin], and dexamethasone)
  • Melphalan plus prednisone

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