What are the signs and symptoms of multiple myeloma (MM)?

Updated: May 11, 2021
  • Author: Dhaval Shah, MD; Chief Editor: Emmanuel C Besa, MD  more...
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MM can range from asymptomatic to severely symptomatic with complications requiring emergent treatment. Presenting signs and symptoms of MM include the following:

  • Bone pain
  • Pathologic fractures
  • Spinal cord compression (from pathologic fracture)
  • Weakness, malaise
  • Bleeding, anemia
  • Infection (often pneumococcal)
  • Hypercalcemia
  • Kidney failure
  • Neuropathies

See Presentation for more detail.

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