What are the characteristic lab findings in monoclonal gammopathy of undetermined significance (MGUS)?

Updated: Dec 29, 2019
  • Author: Suzanne R Fanning, DO; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

MGUS is characterized by the following:

  • Serum M-protein value less than 3 g/dL
  • Fewer than 10% plasma cells in the bone marrow
  • No or only small amounts of Bence-Jones protein in the urine
  • Absence of lytic bone lesions
  • No related anemia, hypercalcemia, renal failure, or any related end-organ damage

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