What are the age-related differences in the incidence of monoclonal gammopathy of undetermined significance (MGUS)?

Updated: Sep 07, 2018
  • Author: Suzanne R Fanning, DO; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Age-related differences in incidence are as follows:

  • The median age of patients with the disease is 70 years; however, most physicians are observing patients younger than this, possibly because of improved screening rather than an increased incidence of the process

  • The incidence of MGUS is higher in older patients than in younger patients; of patients older than 80 years, the available literature suggests as many as 10-15% may have an M-protein


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