What is included in intrapartum antiretroviral therapy (ART) for pregnant women with HIV infection?

Updated: Jun 23, 2020
  • Author: Madhu Chhanda Choudhary, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Answer

Intrapartum AZT should be administered to pregnant HIV-infected women if the HIV viral load is 1000 or more copies/mL or unknown at time of delivery, irrespective of mode of delivery. [23]

AZT 2 mg/kg IV is administered over 1 hour, then continuous infusion of 1 mg/kg/h from onset of labor to delivery.

Oral AZT, if part of the combination regimen, should be stopped while IV AZT is administered.

IV AZT is not required if the patient is receiving combination therapy and the HIV viral load is consistently less than 1000 copies/mL near time of delivery and adherence is reliable.


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