What is the role of tenofovir alafenamide in antiretroviral therapy (ART) for pregnant women with HIV infection?

Updated: Jun 23, 2020
  • Author: Madhu Chhanda Choudhary, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Answer

In the IMPAACT P1026sPK study, among women taking tenofovir alafenamide without cobicistat, tenofovir alafenamide exposure was lower in the third trimester compared with postpartum, whereas no differences were seen between pregnancy and postpartum in women taking tenofovir alafenamide with cobicistat. [22] Before tenofovir alafenamide can be recommended during pregnancy, additional safety and outcome data are needed.


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