Which factors are weighed in the decision to administer antiretroviral therapy (ART) for HIV infection during pregnancy?

Updated: Jun 23, 2020
  • Author: Madhu Chhanda Choudhary, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Answer

Antiretroviral therapy (ART) should be selected based on specific factors, including the following:

  • Comorbidities, especially hepatitis B coinfection
  • Patient adherence and convenience of therapy
  • Potential for adverse drug effects on the mother and drug interactions
  • Results of genotypic resistance testing
  • Safety and pharmacokinetic data in pregnancy
  • Potential teratogenic effects on the fetus and other adverse effects on the fetus or newborn

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