What is the characteristic history of congenital (hereditary) methemoglobinemia?

Updated: Dec 09, 2018
  • Author: Mary Denshaw-Burke, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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The characteristic history in the congenital (hereditary) form of the condition is the presence of diffuse, persistent, slate-gray cyanosis, often present from birth. There is no evidence of cardiopulmonary disease. Patients with hereditary methemoglobinemia are asymptomatic despite the presence of cyanosis. The failure of 100% oxygen to correct cyanosis is very suggestive of methemoglobinemia.

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