What are the racial predilections for methemoglobinemia?

Updated: Dec 09, 2018
  • Author: Mary Denshaw-Burke, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

The congenital form of methemoglobinemia due to cytochrome b5 reductase deficiency (type Ib5R) is endemic in certain ethnic groups. These groups include the Navajo, Athabaskan Alaskans, and the Yakutsk people in Siberia. Because G6PD deficiency is a risk factor for acquired methemoglobinemia, populations in which such deficiency is endemic, including populations of Mediterranean and African descent, are at higher risk for acquired methemoglobinemia.


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