What is the role of dapsone in the etiology of methemoglobinemia?

Updated: Dec 21, 2020
  • Author: Mary Denshaw-Burke, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Dapsone, a drug used to prevent and treat Pneumocystis jiroveci pneumonia (PCP) and to treat leprosy and other skin diseases (including a topical preparation used for acne [31] ), has also been associated with methemoglobinemia. This drug should be used with great caution in patients with known G6PD deficiency, methemoglobin reductase deficiency, or Hb M. [15, 32]

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