What is the role of dapsone in the etiology of methemoglobinemia?

Updated: Dec 09, 2018
  • Author: Mary Denshaw-Burke, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
  • Print
Answer

Dapsone, a drug used to prevent and treat Pneumocystis jiroveci pneumonia (PCP) and to treat leprosy and other skin diseases (including a topical preparation used for acne [29] ), has also been associated with methemoglobinemia. This drug should be used with great caution in patients with known G6PD deficiency, methemoglobin reductase deficiency, or Hb M. [14, 30]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!