Answer
Answer
Lopinavir/ritonavir (LPV/RTV)
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LPV 400 mg/RTV 100 mg per dose BID (adolescent, ≥40 kg)
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Pediatric dose (>6 mo - 18 years): For individuals receiving concomitant nelfinavir (NFV), NVP, EFV, or FPV (these drugs induce LPV metabolism and reduce LPV plasma levels), increased LPV/RTV dosing is required with concomitant administration of these drugs and/or in treatment-experienced patients in whom reduced susceptibility to LPV is suspected (such as those with prior treatment with other protease inhibitors)
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Once-daily dosing is not recommended in adolescents
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