How is rilpivirine (RPV) administered in antiretroviral therapy for HIV infection in adolescents and young adults?

Updated: Mar 16, 2020
  • Author: David J Cennimo, MD, FAAP, FACP, AAHIVS; Chief Editor: Michelle R Salvaggio, MD, FACP  more...
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Answer

Answer

 

Rilpivirine (RPV)

  • Indicated in combination with other antiretroviral agents for treatment of HIV-1 infection in treatment-naïve adolescents aged 12-17 years with HIV-1 RNA ≤100,000 copies/mL (approved by FDA for adolescents in August 2015)
  • 25 mg PO once daily; take with food
  • Complera: Combination formulation including RPV 25 mg/emtricitabine (FTC) 200 mg/tenofovir disoproxil fumarate (TDF) 300 mg; take once daily with food
  • Odefsey: Combination formulation including RPV 25 mg/emtricitabine (FTC) 200 mg/tenofovir alafenamide fumarate (TAF) 25 mg; take once daily with food
  • Juluca: Combination formulation including RPV 25 mg/DTG 50mg; take once daily with food

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