How is efavirenz (EFV) administered in antiretroviral therapy for HIV infection in adolescents and young adults?

Updated: Mar 16, 2020
  • Author: David J Cennimo, MD, FAAP, FACP, AAHIVS; Chief Editor: Michelle R Salvaggio, MD, FACP  more...
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Answer

Answer

Efavirenz (EFV)

  • 600 mg PO once daily (adolescent, ≥40 kg) [10]
  • Atripla: Combination formulation including EFV 600 mg/emtricitabine (FTC) 200 mg/ tenofovir disoproxil fumarate (TDF) 300 mg; 1 tablet PO once daily (drug combination should not be used in pediatric patients, < 40 kg, in whom the EFV dose would be excessive)
  • Symfi Lo: Combination formulation including EFV 600 mg/3TC 300 mg/TDF 300 mg; 1 tablet PO once daily (adolescent, ≥35 kg)

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