When are potassium and calcium replacement indicated in the treatment of hypomagnesemia?

Updated: Oct 30, 2020
  • Author: Tibor Fulop, MD, PhD, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Patients with concomitant hypokalemia or hypocalcemia should also receive potassium and calcium replacement, because these disorders may take several days to correct when treated with magnesium alone. In the presence of hypocalcemia, tetany can occur during the administration of magnesium sulfate if calcium is not supplemented, as ionized calcium levels can drop acutely from complexing of calcium with sulfate ions and increased urinary excretion. [116]

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