How is primary mediastinal B-cell lymphoma (PMBCL) treated?

Updated: Sep 14, 2019
  • Author: Sonali M Smith, MD; Chief Editor: Emmanuel C Besa, MD  more...
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For patients who present with superior vena cava (SVC) syndrome, establishing the diagnosis in a timely and efficient manner is critical. Radiation therapy (RT) can alter the pathologic findings and would impair accurate diagnosis; thus, it should be avoided except in extreme circumstances. Patients who are relatively stable should undergo emergent diagnostic evaluation (as summarized above) followed by treatment initiation. [23]

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