Which physical findings are characteristic of primary mediastinal B-cell lymphoma (PMBCL)?

Updated: Sep 14, 2019
  • Author: Sonali M Smith, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

Physical examination may reveal the following:

  • SVC syndrome, with congestion of face and upper extremities and occasional airway compromise
  • Palpable mass in the supraclavicular area
  • Dullness at the lung bases
  • Respiratory distress, especially with direct extension to the lungs
  • Peripheral adenopathy (unusual except in the supraclavicular area)

Performance status should be noted because this is an important prognostic indicator. [18]


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