What is the role of pulmonary vasodilator drugs in the treatment of tetralogy of Fallot (TOF)?

Updated: Nov 13, 2018
  • Author: Shabir Bhimji, MD, PhD; Chief Editor: Yasmine S Ali, MD, FACC, FACP, MSCI  more...
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Answer

Research is being conducted on drugs that can dilate the pulmonary vasculature and lower the pulmonary insufficiency. Initial studies using nitric oxide suggest that such a strategy may be effiective. Sildenafil has been used to treat such patients, [25] but there are no long-term studies to determine if this agent can prevent progression of the pulmonary insufficiency.


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