What is the role of bone marrow biopsy in the workup of lymphoblastic lymphoma?

Updated: Sep 10, 2019
  • Author: Joseph M Tuscano, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

Complete a bone marrow aspiration and biopsy with studies for cytogenetic and flow cytometric analysis. [13, 14, 15] Bone marrow is involved at presentation in 30-50% of cases of lymphoblastic lymphoma, and lymphoblasts may comprise up to 25% of marrow elements. If lymphoblasts involve more than 25% of the marrow, patients are arbitrarily diagnosed with acute lymphoblastic leukemia (ALL).


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