Which serum chemistry findings are characteristic of non-Hodgkin lymphoma (NHL)?

Updated: Feb 25, 2021
  • Author: Sanjay Vinjamaram, MD, MPH; Chief Editor: Emmanuel C Besa, MD  more...
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Serum chemistry studies may show the following:

  • Elevated lactate dehydrogenase (LDH): indicates poor prognosis; correlates with increased tumor burden

  • Abnormal liver function test (LFT) results: secondary to hepatic involvement, hypermetabolic tumor growth, chronic inflammation

  • Hypercalcemia: in patients with acute form of adult T-cell lymphoma-leukemia (ATLL)

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