Which studies are performed in the diagnostic workup of non-Hodgkin lymphoma (NHL)?

Updated: Feb 25, 2021
  • Author: Sanjay Vinjamaram, MD, MPH; Chief Editor: Emmanuel C Besa, MD  more...
  • Print

The workup in a patient with suspected non-Hodgkin lymphoma (NHL) should include the following:

  • Complete blood cell (CBC) count

  • Serum chemistry studies, including lactate dehydrogenase (LDH)

  • Serum beta2-microglobulin level

  • HIV serology

  • Chest radiography

  • Computed tomography (CT) scan of the neck, chest, abdomen, and pelvis

  • Positron emission tomography (PET) scan

  • Excisional lymph node biopsy

  • Bone marrow aspirate and biopsy

  • Hepatitis B testing in patients in whom rituximab therapy is planned because reactivation has been reported

Other studies may be indicated, depending on the clinical presentation.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!