What is the prevalence of non-Hodgkin lymphoma (NHL)?

Updated: Feb 25, 2021
  • Author: Sanjay Vinjamaram, MD, MPH; Chief Editor: Emmanuel C Besa, MD  more...
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The American Cancer Society estimates that approximately 81,560 new cases of NHL will be diagnosed in 2021. [8]  From the early 1970s to the early 21st century, the incidence rates of NHL nearly doubled. Although some of this increase may be attributable to earlier detection (resulting from improved diagnostic techniques and access to medical care), or possibly to HIV-associated lymphomas, for the most part the rise is unexplained. From 2011 to 2015, incidence rates declined by 0.6% per year; however, patterns vary by subtype. [8]  

NHL is the most prevalent hematopoietic neoplasm, representing approximately 4.3% of all cancer diagnoses and ranking seventh in frequency among all cancers. NHL is more than 5 times as common as Hodgkin disease. [9]

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