When is lumbar puncture indicated in the workup of non-Hodgkin lymphoma (NHL)?

Updated: Feb 25, 2021
  • Author: Sanjay Vinjamaram, MD, MPH; Chief Editor: Emmanuel C Besa, MD  more...
  • Print

Perform lumbar puncture for CSF analysis in patients with the following conditions:

  • Diffuse aggressive NHL with bone marrow, epidural, testicular, paranasal sinus, or nasopharyngeal involvement, or 2 or more extranodal sites of disease

  • High-grade lymphoblastic lymphoma

  • High-grade small noncleaved cell lymphomas

  • HIV-related lymphoma

  • Primary CNS lymphoma

  • Neurologic signs and symptoms

See Workup for more detail.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!