What is the CHOP chemotherapy regimen for mantle cell lymphoma (MCL)?

Updated: Mar 15, 2019
  • Author: Muhammad Rashid Abbasi, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

CHOP is administered every 21 days, in the following regimen:

  • Cyclophosphamide at 750 mg/ 2 IV on day 1
  • Doxorubicin at 50 mg/ 2 IV on day 1
  • Vincristine at 1.4 mg/ 2 IV on day 1, not to exceed 2 mg
  • Prednisone at 100 mg/d PO on days 1-5

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