What are the signs and symptoms of mantle cell lymphoma (MCL)?

Updated: Mar 15, 2019
  • Author: Muhammad Rashid Abbasi, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Findings on the history include the following:

  • Stage IV disease in 70% of patients
  • B symptoms, which include fever, night sweats, and weight loss, in 40% of patients
  • Generalized lymphadenopathy
  • Abdominal distention from hepatosplenomegaly
  • Fatigue from anemia or bulky disease
  • Less common symptoms caused by extranodal involvement of gastrointtestinal (GI) tract, lungs, and central nervous system (CNS)

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