Which chemotherapy regimens have been studied for the treatment of relapsed or refractory mantle cell lymphoma (MCL)?

Updated: Mar 15, 2019
  • Author: Muhammad Rashid Abbasi, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

The following regimens have been studied for relapsed or refractory MCL:

  • R–hyper-CVAD

  • Hyper-CVAD with or without rituximab followed by ASCT

  • Nucleoside analogues and combinations

  • Salvage chemotherapy combinations followed by ASCT

  • Bortezomib (Velcade)

  • Lenalidomide (Revlimid)

  • Ibrutinib (Imbruvica)

  • Radioimmunotherapy

  • Rituximab

  • Rituximab and thalidomide combination

  • High-dose chemotherapy with autologous bone marrow or stem cell transplantation

  • Acalabrutinib (Calquence)


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