What is the role of intrathecal chemotherapy in the treatment of DLBCL?

Updated: Jun 12, 2019
  • Author: Shipra Gandhi, MBBS; Chief Editor: Emmanuel C Besa, MD  more...
  • Print
Answer

Routine intrathecal chemotherapy is strongly recommended in patients with DLBCL with the following characteristics:

  • Two or more extranodal sites of disease

  • Testicular or breast involvement, regardless stage

  • Lymphoblastic variants

  • Oropharyngeal or paraspinal sites of involvement

  • Bone marrow involvement

  • Concomitant infection with the human immunodeficiency virus (HIV)


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!