What is the role of intrathecal chemotherapy in the treatment of diffuse large B-cell lymphoma (DLBCL)?

Updated: Aug 20, 2020
  • Author: Shipra Gandhi, MBBS; Chief Editor: Emmanuel C Besa, MD  more...
  • Print

Routine intrathecal chemotherapy is strongly recommended in patients with DLBCL with the following characteristics:

  • Two or more extranodal sites of disease
  • Testicular or breast involvement, regardless stage
  • Lymphoblastic variants
  • Oropharyngeal or paraspinal sites of involvement
  • Bone marrow involvement
  • Concomitant infection with human immunodeficiency virus (HIV)

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!