How does WHO classify the clinical variants of B-cell Burkitt lymphoma (BL)?

Updated: Feb 23, 2021
  • Author: Mohammad Muhsin Chisti, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
  • Print
Answer

The 2008 World Health Organization classification identifies the following three clinical variants of Burkitt lymphoma (BL) [3] :

  • Endemic (eBL) – The most common form of childhood malignancy in equatorial Africa, associated with Epstein-Barr virus (EBV) infection
  •  Sporadic (sBL) – The majority of cases are in the United States and Europe; up to 30% are associated with EBV
  •  Immunodeficiency associated – Occurs in patients with HIV infection, post-transplantation immunosuppression, and congenital immunodeficiency         

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!