What are the first-line regimens for consolidation or extended dosing in the treatment of B-cell follicular lymphoma?

Updated: Feb 23, 2021
  • Author: Mohammad Muhsin Chisti, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

First-line regimens for consolidation or extended dosing (optional) include the following:

  • Rituximab maintenance – 375 mg/m 2, one dose every 8 to 12 wk for 12 doses, for patients initially presenting with high tumor burden (category 1)
  • Obinutuzumab maintenance – 1000 mg every 8 wk for 12 doses
  • Rituximab consolidation –375 mg/m 2 one dose every 8 weeks for 4 doses If initially treated with single-agent rituximab
  • Ibritumomab tiuxetan (category 2B)

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