Which clinical history findings are characteristic of light-chain deposition disease (LCDD)?

Updated: Sep 26, 2019
  • Author: Swapna Boppana, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Patients are found to have light-chain deposition disease (LCDD) when they are evaluated for proteinuria or nephrotic syndrome by renal biopsy. The common symptoms and signs are related to associated organ involvement and may manifest as renal failure, congestive heart failure, and/or liver failure. Most patients present with advanced disease, owing to a delay in the diagnosis.


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