What is the role of prolonged achlorhydria in the etiology of iron deficiency anemia?

Updated: Sep 07, 2019
  • Author: James L Harper, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Prolonged achlorhydria may produce iron deficiency because acidic conditions are required to release ferric iron from food. Then, it can be chelated with mucins and other substances (eg, amino acids, sugars, amino acids, or amides) to keep it soluble and available for absorption in the more alkaline duodenum.


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