What is the role of nonintestinal cells in iron uptake?

Updated: Sep 07, 2019
  • Author: James L Harper, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Nonintestinal cells also possess the mobilferrin integrin and DMT-1 pathways. Their function in the absence of an iron-saturated transferrin is uncertain; however, their presence in nonintestinal cells suggests that they may participate in intracellular functions in addition to their capability to facilitate cellular uptake of iron.


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