How much iron is concentrated within enterocytes?

Updated: Aug 04, 2019
  • Author: James L Harper, MD; Chief Editor: Emmanuel C Besa, MD  more...
  • Print
Answer

The iron concentration within enterocytes varies directly with the body’s requirement for iron. Absorptive cells of iron-deficient humans and animals contain little stainable iron, whereas those of subjects who are replete in iron contain significantly higher amounts. Untreated phenotypic hemochromatosis creates little stainable iron in the enterocyte, similar to iron deficiency. Iron within the enterocyte may operate by up-regulation of a receptor, saturation of an iron-binding protein, or both.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!