Which cell pathway transports nonheme iron?

Updated: Sep 30, 2020
  • Author: James L Harper, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Which pathway transports most nonheme iron in humans is not known. Most nonheme dietary iron is ferric iron. Iron absorption in mice and rats may involve more ferrous iron because they excrete moderate quantities of ascorbate in intestinal secretions. Humans, however, are a scorbutic species and are unable to synthesize ascorbate to reduce ferric iron.

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