What is the initial treatment of immune thrombocytopenic purpura (ITP)?

Updated: Jun 28, 2019
  • Author: Craig M Kessler, MD, MACP; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

For initial (induction) treatment, in patients with a platelet count of 20-30 × 109/L [20-30 × 103/µL] and/or mucocutaneous bleeding), one regimen is prednisone 4-8 mg/kg/d with the intent of a rapid and complete taper after 7-10 days or when the platelet count reaches 50 × 109/L (50 × 103/µL), whichever occurs first. In critical situations, an IV infusion of a corticosteroid may be preferable.


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