What is the role of corticosteroids in the treatment of immune thrombocytopenia (ITP)?

Updated: Jan 11, 2020
  • Author: Craig M Kessler, MD, MACP; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Answer

The treatment paradigm is now shifting, with expanding experience with earlier use of thrombopoietin receptor analogs (TPO-RA; TPO-mimetics) in chronic ITP. However, this is not yet the standard of care. These agents may not be conducive to preventing or reversing the potential for acute bleeding complications in newly diagnosed ITP, given the delayed platelet count responses they produce. However, data are maturing on their use and long-term effectiveness.

The treatment paradigm is now shifting, with expanding experience with earlier use of thrombopoietin receptor analogs (TPO-RA; TPO-mimetics) in chronic ITP. However, this is not yet the standard of care. These agents may not be conducive to preventing or reversing the potential for acute bleeding complications in newly diagnosed ITP, given the delayed platelet count responses they produce. However, data are maturing on their use and long-term effectiveness.


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