What should be included in the evaluation of the spleen in patients with immune thrombocytopenic purpura (ITP)?

Updated: Jun 28, 2019
  • Author: Craig M Kessler, MD, MACP; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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The spleen reveals no specific findings. In adults, the microscopic finding of extramedullary hematopoiesis is atypical and indicates myeloid metaplasia. Spleens removed from patients with immune thrombocytopenic purpura (ITP) should be carefully examined for a primary splenic lymphoma or granuloma or other signs of an undiagnosed infectious disease.

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